Gabonese Referee Eric Otogo Castane has been appointed to officiate Group F’s final group game between Ghana and Guinea Bissau in Suez on Tuesday.
The Black Stars must win at all cost to enhance their chances of making it into the next round.
Guinea-Bissau are also without a win in their last two games played and will be seeking to upset the Black Stars.
The last time Referee Castane officiated a Black Stars game at the Africa Cup of Nations was in 2015, where Ghana thrashed hosts Equatorial Guinea by 3-0.